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Dr. Eliezer Soto

Eliezer Soto

, MD, DABPMR, DABPM, DABIM, CIPS, FIPP, EDPM

Dr. Eliezer Soto joined the University at Buffalo Neurosurgery in 2026 as an interventional pain physician specializing in the comprehensive management of spine and musculoskeletal pain disorders. Dr. Soto is board-certified in Internal Medicine, Pain Medicine, Internal Medicine, and Hospice & Palliative Medicine. He is also a Fellow of Interventional Pain Practice (FIPP) through the World Institute of Pain, a Certified Interventional Pain Sonologist (CIPS), and a diplomate of the European Diploma in Pain Medicine (EDPM) awarded by the European Pain Federation (EFIC).

He earned his medical degree from the University of Puerto Rico School of Medicine, where he graduated Magna Cum Laude. He completed his internship and residency in Internal Medicine at Mount Auburn Hospital, a Harvard Medical School teaching hospital, followed by a fellowship in Hospice and Palliative Medicine at the National Institutes of Health (NIH). He subsequently completed fellowship training in Anesthesiology-based Interventional Pain Medicine at Mount Sinai Beth Israel in New York City, where he also completed a research fellowship in Pain Medicine and Clinical Research. Dr. Soto is currently pursuing a PhD in Clinical Research at Universidad Complutense de Madrid.

Dr. Soto specializes in the diagnosis and treatment of acute and chronic pain using a comprehensive, multidisciplinary approach. His clinical expertise includes the use of fluoroscopy and ultrasound technology, and endoscopically guided interventional spine and pain procedures. These procedures encompass endoscopic spine interventions, including endoscopic rhizotomy, endoscopic discectomy, and endoscopic spinal decompression; as well as basivertebral nerve ablation, spinal cord stimulation, peripheral nerve stimulation, radiofrequency ablation, sacroiliac joint interventions, vertebral augmentation, regenerative therapies, peripheral joint interventions, and other minimally invasive pain management techniques.

His clinical and research interests include vertebrogenic and discogenic low back pain, minimally invasive spine interventions, endoscopic spine procedures, neuromodulation, regenerative medicine, and translational pain research. He works closely with neurosurgeons, orthopedic spine surgeons, physiatrists, and rehabilitation specialists to develop individualized, evidence-based treatment plans that optimize patient outcomes while minimizing the need for surgery whenever appropriate. 

As an active clinician-scientist, Dr. Soto has authored numerous peer-reviewed publications and book chapters, and has been invited to review articles focusing on vertebrogenic pain, discogenic pain, neuromodulation, minimally invasive spine interventions, and regenerative therapies. His research focuses on advancing evidence-based interventional pain treatments through translational research and prospective clinical studies. He serves as a reviewer for several international pain and spine journals and actively participates in national and international pain societies.

He is committed to delivering compassionate, evidence-based care while advancing innovation, education, and clinical research in interventional pain medicine.

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Interventional Spine and Pain Management Physician

Comprehensive Neuroscience Center

40 George Karl Blvd.
Suite 100
Williamsville, NY 14221

Phone: 716.218.1000

Fax: 716.626.1908; 716.626.1491; 716-633-2679;

Sterling Medical Park

250 Windward Rd., Suite 100
Orchard Park, NY 14127

Phone: 716.218.1000

Fax: 716.634.1690

Atlas Surgery Center

50 George Karl Blvd,
Williamsville, NY 14221

Phone: 716.650.0905

Education

Graduate School

Universidad Complutense de Madrid

Medical School

University of Puerto Rico School of Medicine, Magna Cum Laude

Residency

Mount Auburn Hospital / Harvard Medical School Internal Medicine Residency

Fellowships

National Institutes of Health (NIH) Hospice & Palliative Medicine

Mount Sinai Beth Israel Interventional Pain Medicine/Anesthesiology 

Research: Mount Sinai Beth Israel Pain Medicine & Clinical Research

Social Media

Clinical Expertise & Surgical Interests

Interventional Spine & Pain Medicine

Vertebrogenic and discogenic low back pain, fluoroscopically, ultrasound, and endoscopically guided spine procedures, basivertebral nerve ablation, epidural steroid injections, facet joint injections and medial branch blocks, radiofrequency ablation, sacroiliac joint injections and stabilization, vertebral augmentation, sympathetic nerve blocks, peripheral joint interventions, regenerative medicine, and other minimally invasive spine interventions.

Neuromodulation

Spinal cord stimulation, dorsal root ganglion stimulation, peripheral nerve stimulation, implantable intrathecal drug delivery systems, and comprehensive management of chronic neuropathic, postsurgical, cancer-related, and complex pain conditions.

Endoscopic Spine Procedures

Endoscopic rhizotomy, endoscopic discectomy, endoscopic decompression, and other minimally invasive endoscopic techniques for the treatment of chronic spinal pain.

Clinical & Research Interests

Vertebrogenic pain, discogenic pain, minimally invasive spine interventions, neuromodulation, regenerative medicine, translational pain research, and clinical outcomes research.

Professional Highlights

Dr. Soto has established a national and international reputation in interventional pain medicine through his contributions to clinical care, education, and research. He has authored numerous peer-reviewed publications, book chapters, and invited review articles on vertebrogenic pain, discogenic pain, neuromodulation, minimally invasive spine interventions, and regenerative medicine. He serves as a peer reviewer for several leading pain and spine journals and has presented his research and clinical expertise at national and international scientific meetings. 

Dr. Soto is an active member of several professional organizations, including the American Society of Pain and Neuroscience (ASPN), the International Pain and Spine Intervention Society (IPSIS), the American Society of Interventional Pain Physicians (ASIPP), the International Association for the Study of Pain (IASP), the European Pain Federation (EFIC), the Sociedad Española del Dolor (SED), and the Sociedad Española de Cirugía Percutánea y Endoscópica de Columna (SECPEC). 

He remains committed to advancing physician education, evidence-based clinical practice, and innovation in interventional pain medicine. Dr. Soto is a Fellow of Interventional Pain Practice (FIPP), a Certified Interventional Pain Sonologist (CIPS), and is currently pursuing a PhD in Clinical Research at Universidad Complutense de Madrid, with research focused on advancing minimally invasive spine interventions and improving outcomes for patients with chronic pain.

Certifications

Board Certifications

Internal Medicine

Pain Medicine

Hospice & Palliative Medicine

Professional Certifications

Fellow of Interventional Pain Practice (FIPP)

Certified Interventional Pain Sonologist (CIPS)

European Diploma in Pain Medicine (EDPM)

Dr. Eliezer Soto Publications

Publications | August 4, 2026

Oral ketamine in the palliative care setting: a review of the literature and case report of a patient with neurofibromatosis type 1 and glomus tumor-associated complex regional pain syndrome

Soto E, Stewart D, Mannes A, Ruppert S, Baker K, Zlott D, Handel D, Berger A. Oral Ketamine in the Palliative Care Setting: A Review of the Literature and Case Report of a Patient with NF1 and Glomus Tumor–Associated CRPS. Am J Hosp Palliat Care. 2012;29(4):308-317. [Epub 2011 Jul 29]. Free article: https://pubmed.ncbi.nlm.nih.gov/21803784/

Publications | August 4, 2026

Using Transcranial Direct Current Stimulation to Treat Depression in HIV-Infected Persons: The Outcomes of a Feasibility Study

Knotkova H, Rosedale M, Strauss SM, Horne J, Soto E, Cruciani RA, Malaspina D, Malamud D. Using Transcranial Direct Current Stimulation (tDCS) to Treat Depression in HIV-Infected Persons: Outcomes of a Feasibility Study. Front Psychiatry. 2012;3:59. Free article: https://pmc.ncbi.nlm.nih.gov/articles/PMC3376409/

Publications | August 4, 2026

Transient thermal sympathectomy as a possible mechanism for hypotension after kyphoplasty: a case report

Soto E, Galperin M, Portenoy RK. Thermal Sympathectomy as Possible Mechanism for Persistent Hypotension after Bilateral Kyphoplasty: A Case Report. Clin J Pain. 2013;29(12):e49-53. Free article: https://pubmed.ncbi.nlm.nih.gov/24042346/

Publications | August 4, 2026

Multimodal and simultaneous assessments of brain and spinal fluid abnormalities in chronic fatigue syndrome and the effects of psychiatric comorbidity

Natelson BH, Mao X, Stegner AJ, Lange G, Vu D, Blate M, Kang G, Soto E, Kapusuz T, Shungu DC. Multimodal and simultaneous assessments of brain and spinal fluid abnormalities in chronic fatigue syndrome and the effects of psychiatric comorbidity. J Neurol Sci. 2017;375:411-416. doi:10.1016/j.jns.2017.02.046. Free article: https://pubmed.ncbi.nlm.nih.gov/28320179/